Escherichia coli (named after Theodor Escherich, 1857-1911) is a gram-negative, rod-shaped bacterium. Like all gram-negative bacteria it has an inner and outer membrane. The latter is covered by lipopolysaccharides, LPS, which consist of an O-antigen, a core structure and a lipid A moiety. This database contains structures of the repeating units that comprise the O-antigen and was created during the preparation of a review of E. coli O-antigens by Stenutz, Weintraub and Widmalm.

Items in the database can be accessed in three ways from the menu above. Either the desired item can be selected from a complete listing of the database using List or the database can be searched by any data contained in the records using Search. In addition to this it is possible to browse the database using the Summary Table. This table also shows glycosyltransferase status of each serogroup and gives a statistical summary of the database.

Liu B., Furevi A., Perepelov AV., Guo X., Cao H., Wang Q., Reeves PR., Knirel YA., Wang L., Widmalm G. (2020) Structures and genetics of Escherichia coli O antigen FEMS Microbiol. Rev. 44:655-683.

or

Stenutz R., Weintraub A., Widmalm G. (2006) The structures of Escherichia coli O-polysaccharide antigens FEMS Microbiol. Rev. 30:382-403.

and

Rojas-Macias MA., Ståhle J., Lütteke T., Widmalm G. (2015) Development of the ECODAB into a relational database for Escherichia coli O-antigens and other bacterial polysaccharides Glycobiology 25:341-347.

or

Lundborg M., Modhukur V., Widmalm G. (2010) Glycosyltransferase Functions of E. coli O-antigens Glycobiology 20:366-368.

You may create links to database entries using the database number, e.g. O4, which creates a link to entry 125, i.e. the O4 O-antigen.

Suggestions are welcome. Please send them to: goran.widmalm@su.se

Last updated: 2023-10-24