O-Antigen Description

Serogroup:O105
Serotype H:
Serotype K:
Strain:
Structure:
bDRibf(1->4)aDGlcA(1->2)
                      |   
               ->3)aLRha(1->3)bLRha(1->4)aLRha(1->3)bDGlcNAc(1->
Comment:- Structure from Shigella boydii O11 which is known to be identical to E. coli O105 [1][2]
- Revised structure from [3]
- Sequence may contain O-acetylations but their position are not yet determined [3]
GTs
GT nameDonorAcceptorPosition | Link.NumSimilar to
WbsV

GT NameDonorAcceptorScore / e-value
O120-O120_13


240 / 4e-80
O35-WcnX


126 / 3e-36
O54-O054_07


92 / 9e-24
ncbi CAZy
- Reference [1]
GT nameDonorAcceptorPosition | Link.NumSimilar to
WbsW

GT NameDonorAcceptorScore / e-value
O132-O132_12


89 / 2e-22
ncbi CAZy
- Reference [1]
GT nameDonorAcceptorPosition | Link.NumSimilar to
WbsX

bLRha(1->

GT NameDonorAcceptorScore / e-value
O152-WfgB


147 / 3e-42
O115-WegG

bLRha(1->

->4)bDGlcNAc

143 / 1e-40
ncbi CAZy
- Reference [1]
GT nameDonorAcceptorPosition | Link.NumSimilar to
WbsY

aLRha(1->

->3)bDGlcNAc

GT NameDonorAcceptorScore / e-value
O49-O049_13


305 / 3e-104
O129-RfbG


290 / 2e-98
O135-RfbG


290 / 2e-98
O13-RfbG

aLRha(1->

->3)bDGlcNAc

290 / 2e-98
O150-WfgK


283 / 2e-95
O154-O154_12


280 / 3e-94
O97-O097_05


102 / 9e-27
O154-O154_14


86 / 3e-21
O180-wfcT


85 / 7e-21
O10-O010_11


81 / 1e-19
ncbi CAZy
- Reference [1]
GT nameDonorAcceptorPosition | Link.NumSimilar to
WbsZ

bDRibf(1->

->4)aDGlcA

5 |
ncbi CAZy
- Reference [1]
- Proposed to be a ribosyltransferase for S. boydii O11 [1]. Revised structure [3] would suggest the linkage above.
Non-Sugar Components
- Acetate
Enzymes
FlippaseMSIFNNLKWNTFSQVFKILTQLISIVYLARIIPPNEYGIMAMAGVVMNFASLFRDLGTSA AIIQKEQLQDETKSAVFWLNFLLGFLVFIIITTLTPFISHLYNQPKLLIVLPLLSFSFII SGSSSLHLAMLERESKFFIISKIEVFSAALSLLLAIILANNSFGIYSLVFQSLLNSLSSA VLLWIVSPWRPKGKPRHVINHLKEIFRFTSQLSLFNIINFFARNLDSFLIGKYMSASILG SYNLAYRIMLFPLSSLTFIANRSLYPILSQKKNNYKEINDIYLNTIYIIWFITLPLVTVI TSLNKLFIQVVFGEQWILSADILVWLAPTAIIQSVLSTTGTIFMSQGKTGILLLLGIQGT ILTAVSFMVGIHCGIVDLAKYYFIANAIHFIPCIIFTMKTIKSNILSIFKKTYPLFISAA ISFILISNVRVHFASDIKSLFVLSAIGGTIYLLLLLPISESRKLIKTLQTKIKKR
Trembl: Q6QQW4
PolymeraseMVYGFLWCLCFLLSLFNNNSYFKYYITLCIIMVLWFLASFRGAGVDGDYANYIEYINDAQ SIGYSYRGGYFFDWIVNFFVYIGLPATYVFAVYALAIPIKIKLFQKFSLLSSSILLGYVG FFIYLHDFTQIRAGLAVGIAFWGIYYYAYQNKIKAVILFFASCFIHPSLIFLVAFVCFNK FLSNKLLVVTLMISIILCIINANTFIVQKIVDLSGSADLDLYYRLAVDGQIIKTFGAFPL LNLFISIVSLYYLNNIARENALLSIFIKMLLFSQISWFLFSPIPVLAARISQIFLFSIVF VLPHLSVKLFNQPITIPALYSFVGFLAFIIIAELMHPYQLGF
Trembl: Q6QQW9
Literature
  • First Author: Tao, J. "The O-antigen gene cluster of Shigella boydii O11 and functional identification of its wzy gene". FEMS Microbiology. 234(1). (2004), pp 125-132 PubMed: [15109730]
  • First Author: Lvov, VL. "[Antigenic polysaccharides of Shigella bacteria. Structure of the polysaccharide chain of the lipopolysaccharide from Shigella boydii, type 11].[Article in Russian] ". Bioorg. Khim. 17. (1991), pp 111-120 PubMed: [1712200]
  • First Author: Knirel YA. "Structural Relationships Between Genetically Closely Related O-Antigens of Escherichia coli and Shigella spp.". Biochemistry (Mosc). 81. (2016), pp 600-608 PubMed: [27301288]