Escherichia coli (named after Theodor Escherich, 1857-1911) is a gram-negative, rod-shaped bacterium. Like all gram-negative bacteria it has an inner and outer membrane. The latter is covered by lipopolysaccharides, LPS, which consist of an O-antigen, a core structure and a lipid A moiety. This database contains structures of the repeating units that comprise the O-antigen.
Items in the database can be accessed in three ways from the menu above. Either the desired item can be selected from a complete listing of the database using List or the database can be searched by any data contained in the records using Search. In addition to this it is possible to browse the database using the Summary Table. This table also shows glycosyltransferase status of each serogroup and gives a statistical summary of the database.
This database was created in during the preparation of a review of E. coli O-antigens by Stenutz, Weintraub and Widmalm.
Please cite as: Stenutz R., Weintraub A., Widmalm G. (2006) The structures of Escherichia coli O-polysaccharide antigens.FEMS Microbiol. Rev. 30:382-403.
Additional serogroups have been added and are summarized in a more recent review from 2019 by Liu B. et al..
Please cite as: Liu B., Furevi A., Perepelov AV., Guo X., Cao H., Wang Q., Reeves PR., Knirel YA., Wang L., Widmalm G. (2019) Structures and genetics of Escherichia coli O antigen FEMS Microbiol. Rev. fuz028
Please cite glycosyltransferase information from this database as: Lundborg M., Modhukur V., Widmalm G. (2010)
Glycosyltransferase Functions of E. coli O-antigens. Glycobiology 20:366-368.
Most recent publication covering the above articles: Rojas-Macias MA., Ståhle J., Lütteke T., Widmalm G. (2015) Development of the ECODAB into a relational database for Escherichia coli O-antigens and other bacterial polysaccharides. Glycobiology. doi:10.1093/glycob/cwu116
You may create links to database entries using the database number. E. g. : O4 Creates a link to entry 125, i. e. the O4 antigen.
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Last updated: 2020-10-06